Surface Grafting of Poly(l-glutamates). 2. Helix Orientation
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چکیده
منابع مشابه
On the Geotropic Orientation of Helix
The snail Helix nemoralis in negatively geotropic creeping orients upward upon an inclined surface until the angle of the path of progression (theta) is related to the tilt of the surface (alpha) as (Delta sin theta) (Delta sin alpha) = - const.; theta is very nearly a rectilinear function of log sin alpha. The precision of orientation (P.E.(theta)) declines in proportion to increasing sin alph...
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Transmembrane helices are no longer believed to be just hydrophobic segments that exist solely to anchor proteins to a lipid bilayer, but rather they appear to have the capacity to specify function and structure. Specific interactions take place between hydrophobic segments within the lipid bilayer whereby subtle mutations that normally would be considered innocuous can result in dramatic struc...
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Using a chemical cross-linking procedure, surface-grafted polyglutamate films with a permanently perpendicular helix orientation were prepared. A surface-grafted alpha-helical polyglutamate film containing polymerizable side groups was synthesized by ring-opening terpolymerization of 50 molar% gamma-methyl-L-glutamate N-carboxyanhydride (NCA), 30% gamma-stearyl-L-glutamate NCA and 20% gamma-4-v...
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A key step in transmembrane (TM) signal transduction by G-protein-coupled receptors (GPCRs) is the ligand-induced conformational change of the receptor, which triggers the activation of a guanine nucleotide-binding protein. GPCRs contain a seven-TM helical structure essential for signal transduction in response to a large variety of sensory and hormonal signals. Primary structure comparison of ...
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The ability of helical macrofibers of Bacillus subtilis to convert from left- to right-handed structures or vice versa has been known to be controlled by the nutritional environment (N. H. Mendelson, Proc. Natl. Acad. Sci. U.S.A., 75:2478-2482, 1978). lyt mutants (Ni15, FJ3, FJ6, and FJ7) and also lyt phenocopies of wild-type strain FJ8 were able to undergo helix hand inversion as a function of...
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ژورنال
عنوان ژورنال: Langmuir
سال: 2001
ISSN: 0743-7463,1520-5827
DOI: 10.1021/la001770r